John J. Talley

Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors:  Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1<i>H</i>-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)

Thomas D. Penning, John J. Talley, Stephen R. Bertenshaw et al. · Journal of Medicinal Chemistry · 1997 · 2K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pharmacological analysis of cyclooxygenase-1 in inflammation

Chris Smith, Yan Zhang, Carol M. Koboldt et al. · Proceedings of the National Academy of Sciences · 1998 · 811 citations

Medicine, Biochemistry, Pharmacology +16

4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib:  A Potent and Selective Inhibitor of COX-2

John J. Talley, David Brown, Jeffery S. Carter et al. · Journal of Medicinal Chemistry · 2000 · 643 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life

Jane L. Wang, David C. Limburg, Matthew J. Graneto et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 335 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

<i>N</i>-[[(5-Methyl-3-phenylisoxazol-4-yl)- phenyl]sulfonyl]propanamide, Sodium Salt, Parecoxib Sodium:  A Potent and Selective Inhibitor of COX-2 for Parenteral Administration

John J. Talley, Stephen R. Bertenshaw, David Brown et al. · Journal of Medicinal Chemistry · 2000 · 212 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6