John J. Talley - Concepedia

Author

John J. Talley

Monsanto (United States)

Also Known As

John J Talley, John J. Talley, John Talley

Publications

5.6K

Citations

H-Index

Concepts

All Affiliations

Monsanto (United States)Pfizer (United States)General Electric (United States)Guangzhou Institutes of Biomedicine and Health Chemical Synthesis Lab

About

John J. Talley is an author at Monsanto (United States) specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	17	17	2.8K
2	Natural Sciences	12	12	991
3	Biochemistry	12	12	1.6K
4	Engineering	9	9	343
5	Biomolecular Engineering	2	2	62

John J. Talley

Publications

5.3K

Citations

H-Index

Page 1

	Year	Citations
Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1<i>H</i>-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib) Thomas D. Penning, John J. Talley, Stephen R. Bertenshaw, Journal of Medicinal Chemistry	1997	1.9K
Pharmacological analysis of cyclooxygenase-1 in inflammation Chris Smith, Yan Zhang, Carol M. Koboldt, Proceedings of the National Academy of Sciences InflammationAnti-inflammatoryCox-2-derived PgsSelective Cox-2 InhibitorBiochemistry	1998	808
4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib: A Potent and Selective Inhibitor of COX-2 John J. Talley, David Brown, Jeffery S. Carter, Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistryPharmaceutical ScienceMedicineSelective Inhibitor	2000	642
The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life Jane L. Wang, David C. Limburg, Matthew J. Graneto, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryNovel Benzopyran ClassFavorable Human Half-lifePharmacologyMechanism Of Action	2010	324
<i>N</i>-[[(5-Methyl-3-phenylisoxazol-4-yl)- phenyl]sulfonyl]propanamide, Sodium Salt, Parecoxib Sodium: A Potent and Selective Inhibitor of COX-2 for Parenteral Administration John J. Talley, Stephen R. Bertenshaw, David Brown, Journal of Medicinal Chemistry Pharmaceutical ScienceAltmetric Attention ScorePharmacotherapyChemical BiologyPharmaceutical Chemistry	2000	211
Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere Daniel P. Getman, Gary DeCrescenzo, R. Heintz, Journal of Medicinal Chemistry Pharmaceutical ScienceAltmetric Attention ScorePharmacotherapyAntiviral DrugChemical Biology	1993	178
Synthesis and activity of sulfonamide-substituted 4,5-diaryl thiazoles as selective cyclooxygenase-2 inhibitors Jeffery S. Carter, Steven W. Kramer, John J. Talley, Bioorganic & Medicinal Chemistry Letters Sulfonamide-substituted 4,5-Diaryl ThiazolesMedicinal ChemistryHeterocyclicBiochemistryNatural Sciences	1999	158
Cyanohydrins - a general synthesis Paul G. Gassman, John J. Talley Tetrahedron Letters BiochemistryNatural SciencesDiversity-oriented SynthesisOrganic ChemistryGeneral Synthesis	1978	124
Radiosynthesis, in vitro validation, and in vivo evaluation of 18F-labeled COX-1 and COX-2 inhibitors. Timothy J. McCarthy, Ahmed U Sheriff, Matthew J. Graneto, PubMed	2002	77
Stereospecific intramolecular Diels-Alder reaction of an o-quinone methide John J. Talley The Journal of Organic Chemistry O-quinone MethideEngineeringAltmetric Attention ScoreBibliometricsOrganic Chemistry	1985	64

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