Concepedia

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Jun Fujimoto, Takaharu Hirayama, Yasuhiro Hirata, Yukiko Hikichi, Saomi Murai, Maki Hasegawa, Yuka Hasegawa, Kazuko Yonemori, Akito Hata, Kazunobu Aoyama,

Bioorganic & Medicinal Chemistry · 2017 · 23 citations · 14 references

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14

A small molecule–kinase interaction map for clinical kinase inhibitors

Miles A. Fabian, William Biggs, Daniel K. Treiber et al. · Nature Biotechnology · 2005 · 1.9K citations · Full text

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CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

Ron Firestein, Adam J. Bass, So Young Kim et al. · Nature · 2008 · 679 citations · Full text

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CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response

Joanna Bancerek, Zachary C. Poss, Iris Steinparzer et al. · Immunity · 2013 · 289 citations · Full text

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Synthesis and structural analysis of 2-quinuclidonium tetrafluoroborate

Kousuke Tani, Brian M. Stoltz · Nature · 2006 · 275 citations

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Cyclin C is a haploinsufficient tumour suppressor

Na Li, Anne Fassl, Joel M. Chick et al. · Nature Cell Biology · 2014 · 165 citations · Full text

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