Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.

Michihiro Mutoh, Kouji Watanabe, Tomohiro Kitamura, +12

PubMed

InflammationMouse Colon CarcinogenesisAnti-inflammatoryColon CarcinogenesisChemoprevention Strategy +12

Synthesis and structural analysis of 2-quinuclidonium tetrafluoroborate

Kousuke Tani, Brian M. Stoltz

Nature

Inorganic ChemistryEngineeringStructural AnalysisFluorous SynthesisChemistry +1

Enantioselective Decarboxylative Alkylation Reactions: Catalyst Development, Substrate Scope, and Mechanistic Studies

Douglas C. Behenna, Justin T. Mohr, Nathaniel H. Sherden, +16

Chemistry - A European Journal

Prochiral Enolateα-Quaternary KetonesMechanistic StudiesPalladium CenterEngineering +9

A Facile and Modular Synthesis of Phosphinooxazoline Ligands

Kousuke Tani, Douglas C. Behenna, Ryan M. L. McFadden, +1

Organic Letters

Inorganic ChemistryChemical EngineeringPhosphine/aryl HalideEngineeringCoordination Complex +7

Design and Synthesis of a Highly Selective EP2-Receptor Agonist

Kousuke Tani, Atsushi Naganawa, Akiharu Ishida, +9

Bioorganic & Medicinal Chemistry Letters

Functional SelectivityMedicineReceptor (Biochemistry)Pharmacological AgentPharmacotherapy +2

Combined effects of prostaglandin E receptor subtype EP₁ and subtype EP₄ antagonists on intestinal tumorigenesis in <i>adenomatous polyposis coli</i> gene knockout mice

Tomohiro Kitamura, Masaki Itoh, Tetsuo Noda, +7

Cancer Science

Palladiurn(<scp>0</scp>)-catalysed transfer hydrogenation of alkynes to cis-alkenes with HCO₂H–NEt₃

Kousuke Tani, Naoya Ono, Sentaro Okamoto, +1

Journal of the Chemical Society Chemical Communications

Chemical EngineeringTransfer HydrogenationEngineeringCross-coupling ReactionOrganic Chemistry +7

Synthesis of optically active furfuryl alcohols and butenolides from trans-1-trimethylsilyl-3-alken-1-ynes via successive asymmetric dihydroxylation and hydromagnesiation reactions

Kousuke Tani, Yoshitaka Sato, Sentaro Okamoto, +1

Tetrahedron Letters

EngineeringSuccessive Asymmetric DihydroxylationOrganic ChemistryHydromagnesiation ReactionsSynthetic Chemistry +6

Synthesis of 2-Quinuclidonium by Eliminating Water:  Experimental Quantification of the High Basicity of Extremely Twisted Amides

Tony Ly, Michael R. Krout, Don K. Pham, +3

Journal of the American Chemical Society

Cross-coupling ReactionEngineeringGas PhaseExperimental QuantificationTwisted Amide +8

Novel four selective agonists for prostaglandin E receptor subtypes

Hiroshi Yamamoto, Takayuki Maruyama, Kiyoto Sakata, +8

Prostaglandins & Other Lipid Mediators

Signal TransductionBiochemistryG Protein-coupled ReceptorMedicineFunctional Selectivity +5