Yuka Hasegawa

Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response

Akito Nakamura, Tadahiro Nambu, Shunsuke Ebara et al. · Proceedings of the National Academy of Sciences · 2018 · 170 citations · Full text

Medicine, Oncology, Pharmacology +16

Design and synthesis of selective CDK8/19 dual inhibitors: Discovery of 4,5-dihydrothieno[3′,4′:3,4]benzo[1,2-d]isothiazole derivatives

Koji Ono, Hiroshi Banno, Masanori Okaniwa et al. · Bioorganic & Medicinal Chemistry · 2017 · 37 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +12

Substrate preference of citrus naringenin rhamnosyltransferases and their application to flavonoid glycoside production in fission yeast

Takao Ohashi, Yuka Hasegawa, Ryo Misaki et al. · Applied Microbiology and Biotechnology · 2015 · 31 citations

Life Sciences, Biochemistry, Biotechnology +15

Non-invasive detection of language-related prefrontal high gamma band activity with beamforming MEG

Hiroaki Hashimoto, Yuka Hasegawa, Toshihiko Araki et al. · Scientific Reports · 2017 · 29 citations · Full text

Language Studies, Linguistics, Neuroscience +15

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Jun Fujimoto, Takaharu Hirayama, Yasuhiro Hirata et al. · Bioorganic & Medicinal Chemistry · 2017 · 23 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10