Akito Nakamura

Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response

Akito Nakamura, Tadahiro Nambu, Shunsuke Ebara et al. · Proceedings of the National Academy of Sciences · 2018 · 160 citations · Full text

Tumor Biology, Oncology, Amino Acid Response +14

Antitumor Activity of the Selective Pan-RAF Inhibitor TAK-632 in BRAF Inhibitor-Resistant Melanoma

Akito Nakamura, Takeo Arita, Shuntarou Tsuchiya et al. · Cancer Research · 2013 · 122 citations

Antitumor Activity, Raf Dimer, Tumor Biology +16

Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of <i>C</i>-7-Substituted 1,3-Benzothiazole Derivatives

Masanori Okaniwa, Masaaki Hirose, Takeo Arita et al. · Journal of Medicinal Chemistry · 2013 · 111 citations · Full text

The SUMOylation inhibitor subasumstat potentiates rituximab activity by IFN1-dependent macrophage and NK cell stimulation

Akito Nakamura, Stephen Grossman, Keli Song et al. · Blood · 2022 · 66 citations · Full text

CDK8/19 inhibition induces premature G1/S transition and ATR-dependent cell death in prostate cancer cells

Akito Nakamura, Daisuke Nakata, Yuichi Kakoi et al. · Oncotarget · 2018 · 47 citations · Full text