Masanori Okaniwa

Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor

Vanessa Rodrik-Outmezguine, Masanori Okaniwa, Zhan Yao et al. · Nature · 2016 · 469 citations

Medicine, Mtor Resistance Mutations, Molecular Biology +4

STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity

Eric L. Dane, Alexis Belessiotis‐Richards, Coralie M. Backlund et al. · Nature Materials · 2022 · 297 citations · Full text

Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells

Akihiro Ohashi, Momoko Ohori, Kenichi Iwai et al. · Nature Communications · 2015 · 197 citations · Full text

A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma

Qi-Wen Fan, Ozlem Aksoy, Robyn A. Wong et al. · Cancer Cell · 2017 · 176 citations

Neuro-oncology, Radiation Oncology, Kinase Inhibitor +8

Antitumor Activity of the Selective Pan-RAF Inhibitor TAK-632 in BRAF Inhibitor-Resistant Melanoma

Akito Nakamura, Takeo Arita, Shuntarou Tsuchiya et al. · Cancer Research · 2013 · 122 citations

Antitumor Activity, Raf Dimer, Tumor Biology +16