Concepedia

Cdk Inhibitors

CDK Inhibitors is a class of regulatory proteins that function as negative regulators of the cell cycle by specifically binding to and inhibiting cyclin-dependent kinase complexes, thereby preventing aberrant cell proliferation.

3.1K

Publications

251.8K

Citations

19.2K

Authors

2.9K

Institutions

Publications per year

2017–2026

904

Parents

Publications

3.1K

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper · Cell · 1993 · 5.7K citations

, , +14

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

Kornélia Polyák, Mong-Hong Lee, Hediye Erdjument‐Bromage et al. · Cell · 1994 · 2.1K citations

, , +15

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

Hideo Toyoshima, Tony Hunter · Cell · 1994 · 2.1K citations

, , +13

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

Kornélia Polyák, Jun‐ya Kato, Michael J. Solomon et al. · Genes & Development · 1994 · 2K citations · Full text

, , +17

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

Tsutomu Nobori, Kaoru Miura, David Wu et al. · Nature · 1994 · 1.8K citations

, , +14

1–5 of 3.1K

Authors

19.2K

  1. LM
    Laurent Meijer

    Station Biologique de Roscoff, France

    61 publications · 9.5K citations

    43

    h-index

  2. NS
    Nathanael S. Gray

    Dana-Farber Cancer Institute, United States

    39 publications · 6.1K citations

    31

    h-index

  3. PM
    Peter M. Fischer

    University of Nottingham, United Kingdom

    23 publications · 1.7K citations

    20

    h-index

  4. SW
    Shudong Wang

    University of South Australia, Australia

    24 publications · 1.5K citations

    19

    h-index

  5. YX
    Yue Xiong

    University of North Carolina at Chapel Hill, United States

    18 publications · 3.2K citations

    18

    h-index

1–5 of 19.2K

Institutions

2.9K

  1. Harvard University

    Cambridge, United States

    69 h-index

    120 publications

    18.4K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    61 h-index

    77 publications

    24.6K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    60 h-index

    107 publications

    15.1K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    48 h-index

    91 publications

    9.9K citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    40 h-index

    59 publications

    15.4K citations

  6. The University of Texas MD Anderson Cancer Center

    Houston, United States

    39 h-index

    80 publications

    4.8K citations

  7. Cornell University

    Ithaca, United States

    34 h-index

    49 publications

    5.6K citations

  8. Massachusetts General Hospital

    Boston, United States

    32 h-index

    44 publications

    7.2K citations

1–8 of 2.9K

Venues

  1. Journal of Biological Chemistry

    JBC · 123 publications · 11.8K citations

    64

    h-index

  2. Molecular and Cellular Biology

    MCB · 74 publications · 10.8K citations

    56

    h-index

  3. Journal of Medicinal Chemistry

    92 publications · 8.1K citations

    56

    h-index

  4. PubMed

    Repository · 138 publications · 10.2K citations

    55

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 56 publications · 10.1K citations

    48

    h-index

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