Kazuko Yonemori

Cryo-EM Structure of K+-Bound hERG Channel Complexed with the Blocker Astemizole

Tatsuki Asai, Naruhiko Adachi, Toshio Moriya et al. · Structure · 2021 · 95 citations

Natural Sciences, Cell Biology, Molecular Biology +16

Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d

Satoshi Sogabe, Yusuke Kamada, Masanori Miwa et al. · ACS Medicinal Chemistry Letters · 2017 · 83 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Discovery of [<i>cis</i>-3-({(5<i>R</i>)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1<i>H</i>-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5<i>H</i>)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist

Mitsunori Kono, Atsuko Ochida, Tsuneo Oda et al. · Journal of Medicinal Chemistry · 2018 · 63 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2

Misa Iwatani-Yoshihara, Masahiro Ito, Michael G. Klein et al. · Journal of Medicinal Chemistry · 2017 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +15

Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging

Ayumu Niida, Shigekazu Sasaki, Kazuko Yonemori et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 42 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14