Misa Iwatani-Yoshihara

CETSA quantitatively verifies in vivo target engagement of novel RIPK1 inhibitors in various biospecimens

Tsuyoshi Ishii, Takuro Okai, Misa Iwatani-Yoshihara et al. · Scientific Reports · 2017 · 49 citations · Full text

Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2

Misa Iwatani-Yoshihara, Masahiro Ito, Michael G. Klein et al. · Journal of Medicinal Chemistry · 2017 · 41 citations · Full text

Engineering, Rna Structure Prediction, Rna Biology +12

Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay

Misa Iwatani-Yoshihara, Masahiro Ito, Yoshihiro Ishibashi et al. · ACS Chemical Biology · 2017 · 37 citations · Full text

Molecular Biology, Nonsense-mediated Mrna Decay, Chemical Biology +17

Discovery of Novel 1,4-Diacylpiperazines as Selective and Cell-Active eIF4A3 Inhibitors

Masahiro Ito, Toshio Tanaka, Douglas R. Cary et al. · Journal of Medicinal Chemistry · 2017 · 36 citations · Full text

Drug Target, Molecular Biology, Pharmacotherapy +17

Discovery of Novel 5-(Piperazine-1-carbonyl)pyridin-2(1<i>H</i>)-one Derivatives as Orally eIF4A3-Selective Inhibitors

Ryo Mizojiri, Daisuke Nakata, Yoshihiko Satoh et al. · ACS Medicinal Chemistry Letters · 2017 · 13 citations · Full text