Mitsunori Kono

Discovery of [<i>cis</i>-3-({(5<i>R</i>)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1<i>H</i>-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5<i>H</i>)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist

Mitsunori Kono, Atsuko Ochida, Tsuneo Oda et al. · Journal of Medicinal Chemistry · 2018 · 63 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of the First Potent and Orally Available Agonist of the Orphan G-Protein-Coupled Receptor 52

Masaki Setoh, Naoki Ishii, Mitsunori Kono et al. · Journal of Medicinal Chemistry · 2014 · 58 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Synthesis, SAR study, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase (FAAH) inhibitors

Mitsunori Kono, Takahiro Matsumoto, Tōru Kawamura et al. · Bioorganic & Medicinal Chemistry · 2012 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Pharmacological inhibitory profile of TAK-828F, a potent and selective orally available RORγt inverse agonist

Akira Shibata, Keiko Uga, Takayuki Sato et al. · Biochemical Pharmacology · 2018 · 31 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Identification of novel quinazolinedione derivatives as RORγt inverse agonist

Yoshiyuki Fukase, Ayumu Sato, Yoshihide Tomata et al. · Bioorganic & Medicinal Chemistry · 2017 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8