Yoshiyuki Fukase

Divergent synthesis and biological activities of lipid A analogues of shorter acyl chains

Koichi Fukase, Yoshiyuki Fukase, Masato Oikawa et al. · Tetrahedron · 1998 · 76 citations

Shorter Acyl Chains, Biosynthesis, Engineering +6

Discovery of [<i>cis</i>-3-({(5<i>R</i>)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1<i>H</i>-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5<i>H</i>)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist

Mitsunori Kono, Atsuko Ochida, Tsuneo Oda et al. · Journal of Medicinal Chemistry · 2018 · 62 citations

Pharmacotherapy, Pharmaceutical Chemistry, Pre-clinical Pharmacology +16

Structural basis for endotoxic and antagonistic activities: investigation with novel synthetic lipid A analogs

Shoichi Kusumoto, Koichi Fukase, Yoshiyuki Fukase et al. · Journal of Endotoxin Research · 2003 · 43 citations

Lipid Preparation, Medicinal Chemistry, Biosynthesis +15

Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action

Jonathan B. Steinman, Cristina Santarossa, Rand M. Miller et al. · eLife · 2017 · 40 citations · Full text

Combinatorial Chemistry, Unique Mode, Molecular Biology +23

Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules

Kamini Singh, Jianan Lin, Nicolas Lecomte et al. · Cancer Research · 2021 · 34 citations · Full text

Molecular Regulation, Tumor Biology, Deadly Cancer +17