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Tri-Institutional Therapeutics Discovery Institute

TT

Statistics

Publications

133

Citations

13.1K

Authors

14

Location

New York, United States

Also known as Tri-I TDI

Tri-Institutional Therapeutics Discovery Institute is a facility institution in New York, United States known for medicine, natural sciences, and biochemistry.

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Publications

133

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

Jessica Vincent, Carolina Adura, Pu Gao et al. · Nature Communications · 2017 · 360 citations · Full text

, , +21

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Lodoe Lama, Carolina Adura, Wei Xie et al. · Nature Communications · 2019 · 269 citations · Full text

Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation

Wei Xie, Lodoe Lama, Carolina Adura et al. · Proceedings of the National Academy of Sciences · 2019 · 192 citations · Full text

Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues

Nathaniel R. Kastan, Ksenia Gnedeva, Theresa Alisch et al. · Nature Communications · 2021 · 180 citations · Full text

Enhancing Hit Discovery in Virtual Screening through Absolute Protein–Ligand Binding Free-Energy Calculations

Wei Chen, Di Cui, Steven V. Jerome et al. · Journal of Chemical Information and Modeling · 2023 · 110 citations

1–5 of 133

Authors

14

  1. IC
    Ivo C. Lorenz

    Tri-Institutional Therapeutics Discovery Institute, United States

    59 publications · 1.7K citations

    21

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  2. JD
    John D. Ginn

    Tri-Institutional Therapeutics Discovery Institute, United States

    42 publications · 746 citations

    17

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  3. RH
    Ryoma Hara

    Tri-Institutional Therapeutics Discovery Institute, United States

    26 publications · 890 citations

    13

    h-index

  4. RO
    Rei Okamoto

    Tri-Institutional Therapeutics Discovery Institute, United States

    28 publications · 1.1K citations

    13

    h-index

  5. TY
    Takafumi Yukawa

    Tri-Institutional Therapeutics Discovery Institute, United States

    20 publications · 316 citations

    10

    h-index

1–5 of 14