Nathaniel R. Kastan

Disruption of DNA-methylation-dependent long gene repression in Rett syndrome

Harrison W. Gabel, Benyam Kinde, Hume Stroud et al. · Nature · 2015 · 602 citations · Full text

Chromatin, Rett Syndrome, Genetics +6

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

Matthew J. Lyst, Robert Ekiert, Daniel H. Ebert et al. · Nature Neuroscience · 2013 · 397 citations · Full text

Signal Transduction, Mendelian Disorder, Rett Syndrome Mutations +7

Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR

Daniel H. Ebert, Harrison W. Gabel, Nathaniel D. Robinson et al. · Nature · 2013 · 224 citations · Full text

Signal Transduction, Molecular Physiology, Molecular Neuroscience +13

Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues

Nathaniel R. Kastan, Ksenia Gnedeva, Theresa Alisch et al. · Nature Communications · 2021 · 180 citations · Full text

Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs

Nathaniel R. Kastan, Sanyukta Oak, Rui Liang et al. · Proceedings of the National Academy of Sciences · 2022 · 53 citations · Full text

Regeneration, Aids Regeneration, Chemical Modification +20