Rei Okamoto

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

Jessica Vincent, Carolina Adura, Pu Gao et al. · Nature Communications · 2017 · 360 citations · Full text

Primary Macrophages, Innate Immune System, Immunology +21

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Lodoe Lama, Carolina Adura, Wei Xie et al. · Nature Communications · 2019 · 269 citations · Full text

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

Laura A. Kirkman, Wenhu Zhan, Joseph E. Visone et al. · Proceedings of the National Academy of Sciences · 2018 · 97 citations · Full text

Simple Construction of Bicyclo[4.3.0]nonane, Bicyclo[3.3.0]octane, and Related Benzo Derivatives by Palladium-Catalyzed Cycloalkenylation

Masahiro Toyota, Andivelu Ilangovan, Rei Okamoto et al. · Organic Letters · 2002 · 63 citations

Development of a Highly Selective <i>Plasmodium falciparum</i> Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice

Wenhu Zhan, Hao Zhang, John D. Ginn et al. · Angewandte Chemie International Edition · 2021 · 38 citations · Full text