Wenhu Zhan

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

Laura A. Kirkman, Wenhu Zhan, Joseph E. Visone et al. · Proceedings of the National Academy of Sciences · 2018 · 97 citations · Full text

Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes

Ruda de Luna Almeida Santos, Lin Bai, Pradeep K. Singh et al. · Nature Communications · 2017 · 58 citations · Full text

Integrating docking scores, interaction profiles and molecular descriptors to improve the accuracy of molecular docking: Toward the discovery of novel Akt1 inhibitors

Wenhu Zhan, Da-Qiang Li, Jinxin Che et al. · European Journal of Medicinal Chemistry · 2014 · 51 citations · Full text

Medicinal Chemistry, Drug Target, Engineering +11

Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by ¹⁹F NMR and Cryo-EM

Yun Huang, Krishna D. Reddy, Clay Bracken et al. · Journal of the American Chemical Society · 2023 · 39 citations · Full text

Development of a Highly Selective <i>Plasmodium falciparum</i> Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice

Wenhu Zhan, Hao Zhang, John D. Ginn et al. · Angewandte Chemie International Edition · 2021 · 38 citations · Full text