Wei Xie

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

Yijie Gao, David O. Ferguson, Wei Xie et al. · Nature · 2000 · 581 citations

Tumor Biology, Genome Instability, Chromatin +12

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Lodoe Lama, Carolina Adura, Wei Xie et al. · Nature Communications · 2019 · 269 citations · Full text

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Yuanming Cheng, Wei Xie, Brian F. Pickering et al. · Cancer Cell · 2021 · 233 citations · Full text

Phase-separated Nuclear Body, Chromatin, Myeloid Leukemic Differentiation +11

Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation

Wei Xie, Lodoe Lama, Carolina Adura et al. · Proceedings of the National Academy of Sciences · 2019 · 192 citations · Full text

A-type Lamins Form Distinct Filamentous Networks with Differential Nuclear Pore Complex Associations

Wei Xie, Alexandre Chojnowski, Thomas Boudier et al. · Current Biology · 2016 · 151 citations · Full text

Biophysical Modeling, Molecular Biology, Nuclear Organization +6