Brian F. Pickering

m6A RNA methylation promotes XIST-mediated transcriptional repression

Deepak P. Patil, Chun‐Kan Chen, Brian F. Pickering et al. · Nature · 2016 · 1.7K citations · Full text

Transcriptional Regulation, M6a Rna Methylation, Gene Expression +4

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

Ly Vu, Brian F. Pickering, Yuanming Cheng et al. · Nature Medicine · 2017 · 1.3K citations · Full text

Hematological Malignancy, Chromatin, Myeloid Differentiation +12

Reversible methylation of m6Am in the 5′ cap controls mRNA stability

Jan Mauer, Xiaobing Luo, Alexandre Blanjoie et al. · Nature · 2016 · 1.1K citations · Full text

Transcriptional Regulation, Reversible Methylation, Medicine +12

m6A enhances the phase separation potential of mRNA

Ryan J. Ries, Sara Zaccara, Pierre Klein et al. · Nature · 2019 · 692 citations

Natural Sciences, Rna Biology, Molecular Biology +4

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Yuanming Cheng, Wei Xie, Brian F. Pickering et al. · Cancer Cell · 2021 · 233 citations · Full text

Phase-separated Nuclear Body, Chromatin, Myeloid Leukemic Differentiation +11