Kazunobu Aoyama

Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors

Jumpei Aida, Makoto Fushimi, Tomokazu Kusumoto et al. · Journal of Medicinal Chemistry · 2018 · 64 citations · Full text

Magl Enzyme, Medicinal Chemistry, Piperazinyl Pyrrolidin-2-one Core +15

Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and in Vivo

Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama et al. · Drug Metabolism and Disposition · 2008 · 63 citations

Discovery of the First Potent and Orally Available Agonist of the Orphan G-Protein-Coupled Receptor 52

Masaki Setoh, Naoki Ishii, Mitsunori Kono et al. · Journal of Medicinal Chemistry · 2014 · 54 citations · Full text

Psychopharmacology, Pharmacotherapy, Social Sciences +19

Design, Synthesis, and Evaluation of (4<i>R</i>)-1-{3-[2-(¹⁸F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([¹⁸F]<b>T-401</b>) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase

Yasushi Hattori, Kazunobu Aoyama, Jun Maeda et al. · Journal of Medicinal Chemistry · 2019 · 38 citations

Design and synthesis of selective CDK8/19 dual inhibitors: Discovery of 4,5-dihydrothieno[3′,4′:3,4]benzo[1,2-d]isothiazole derivatives

Koji Ono, Hiroshi Banno, Masanori Okaniwa et al. · Bioorganic & Medicinal Chemistry · 2017 · 36 citations · Full text