Hiroaki Yashiro

An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)

Michèle Vacca, Ioannis Kamzolas, Lea Mørch Harder et al. · Nature Metabolism · 2024 · 183 citations · Full text

The Effects of TAK-875, a Selective G Protein-Coupled Receptor 40/Free Fatty Acid 1 Agonist, on Insulin and Glucagon Secretion in Isolated Rat and Human Islets

Hiroaki Yashiro, Yoshiyuki Tsujihata, Koji Takeuchi et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 85 citations

Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis

Emma L. Shepherd, Raquel Saborano, Ellie Northall et al. · JHEP Reports · 2020 · 65 citations · Full text

Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors

Yoshito Terao, Hideo Suzuki, Masato Yoshikawa et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 63 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +13

Discovery of a 3-Pyridylacetic Acid Derivative (TAK-100) as a Potent, Selective and Orally Active Dipeptidyl Peptidase IV (DPP-4) Inhibitor

Yasufumi Miyamoto, Yoshihiro Banno, Tatsuhiko Fujimoto et al. · Journal of Medicinal Chemistry · 2011 · 54 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Pharmacotherapy +16