The Effects of TAK-875, a Selective G Protein-Coupled Receptor 40/Free Fatty Acid 1 Agonist, on Insulin and Glucagon Secretion in Isolated Rat and Human Islets

Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40

Yasuaki Itoh, Yuji Kawamata, Masataka Harada et al. · Nature · 2003 · 1.5K citations

Life Sciences, Cell Biology, Endocrinology +16

Automated Method for Isolation of Human Pancreatic Islets

Camillo Ricordi, Paul E. Lacy, EDWARD H. FINKE et al. · Diabetes · 1988 · 1.3K citations

Medicine, Endocrinology, Physiology +15

ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis

Takashi Miki, Birgit Liss, Kohtaro Minami et al. · Nature Neuroscience · 2001 · 509 citations

Life Sciences, Neuroscience, Physiology +14

Voltage-Gated Ion Channels in Human Pancreatic β-Cells: Electrophysiological Characterization and Role in Insulin Secretion

Matthias Braun, Reshma Ramracheya, Martin Bengtsson et al. · Diabetes · 2008 · 419 citations

Natural Sciences, Endocrinology, Physiology +17

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

Celia P. Briscoe, Andrew J. Peat, Stephen C. McKeown et al. · British Journal of Pharmacology · 2006 · 400 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17