Peptides from water buffalo cheese whey induced senescence cell death <i>via</i> ceramide secretion in human colon adenocarcinoma cell line

Abstract

The structural characterization of the active peptide fraction and the elucidation of the effects induced by its treatment on H-CaCo2 cells in vitro demonstrated an activity of this peptide sub-fraction in the modulation of cell cycle, thus suggesting potential application for the development of nutraceuticals as well as health-promoting functional foods.