Aldo Di Leonardo

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.

Aldo Di Leonardo, Steven P. Linke, Kristie Clarkin et al. · Genes & Development · 1994 · 1.2K citations · Full text

Normal Human Fibroblasts, Dna Damage, Pathology +20

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

Steven P. Linke, Kristie Clarkin, Aldo Di Leonardo et al. · Genes & Development · 1996 · 543 citations · Full text

Dna Damage, Chemoprevention Strategy, Apoptosis +21

DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function.

Aldo Di Leonardo, Shireen Hussain Khan, Steven P. Linke et al. · PubMed · 1997 · 200 citations

Prb Tumor Suppressors, Molecular Biology, Cell Cycle +20

CENPA overexpression promotes genome instability in pRb-depleted human cells

Angela Amato, Tiziana Schillaci, Laura Lentini et al. · Molecular Cancer · 2009 · 136 citations · Full text

The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells

Antonino B. D’Assoro, T Liu, Cosima Quatraro et al. · Oncogene · 2013 · 127 citations · Full text

Epithelial-to-mesenchymal Transition, Cell Regulation, Medicine +10