Concepedia

Protein Lyophilization

Protein Lyophilization is a specialized form of lyophilization that involves the removal of water from protein-based formulations through sublimation under controlled vacuum and low-temperature conditions to preserve structural integrity and biological activity.

806

Publications

42.3K

Citations

2.6K

Authors

777

Institutions

Publications per year

2017–2026

174

Variants

Lyophilization Of Proteins

Parents

Children

Publications

806

Challenges in the development of high protein concentration formulations

Zahra Shahrokh, Jun 军 Liu 刘 · Journal of Pharmaceutical Sciences · 2004 · 879 citations

, , +12

Radioiodination of proteins in single polyacrylamide gel slices. Tryptic peptide analysis of all the major members of complex multicomponent systems using microgram quantities of total protein.

John H. Elder, R. A. Pickett, J W Hampton et al. · Journal of Biological Chemistry · 1977 · 777 citations · Full text

, , +12

The mechanism of cryoprotection of proteins by solutes

John F. Carpenter, John H. Crowe · Cryobiology · 1988 · 555 citations

, , +7

Infrared Spectroscopic Studies of Lyophilization‐ and Temperature‐Induced Protein Aggregation

Aichun Dong, Steven J. Prestrelski, Steven Allison et al. · Journal of Pharmaceutical Sciences · 1995 · 457 citations

, , +14

On Protein Denaturation in Aqueous−Organic Mixtures but Not in Pure Organic Solvents

Kai Griebenow, Alexander M. Klibanov · Journal of the American Chemical Society · 1996 · 400 citations

, , +14

1–5 of 806

Authors

2.6K

  1. JF
    John F. Carpenter

    University of Colorado Boulder, United States

    29 publications · 3.4K citations

    24

    h-index

  2. MJ
    Michael J. Pikal

    University of Connecticut, United States

    21 publications · 1.3K citations

    19

    h-index

  3. KG
    Kai Griebenow

    University of Puerto Rico at Río Piedras, Puerto Rico

    18 publications · 2.1K citations

    17

    h-index

  4. HR
    Henry R. Costantino

    Massachusetts Institute of Technology, United States

    15 publications · 1.7K citations

    15

    h-index

  5. TW
    Theodore W. Randolph

    University of Colorado Boulder, United States

    16 publications · 984 citations

    15

    h-index

1–5 of 2.6K

Institutions

777

  1. University of Connecticut

    Storrs, United States

    23 h-index

    60 publications

    3K citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    20 h-index

    63 publications

    6.3K citations

  3. National Institute of Health Sciences

    Tokyo, Japan

    20 h-index

    69 publications

    3.4K citations

  4. University of Colorado Health

    Aurora, United States

    18 h-index

    36 publications

    4K citations

  5. Amgen (United States)

    Thousand Oaks, United States

    17 h-index

    63 publications

    5K citations

  6. Purdue University West Lafayette

    West Lafayette, United States

    17 h-index

    60 publications

    2K citations

  7. University of Colorado Boulder

    Boulder, United States

    16 h-index

    36 publications

    5.3K citations

  8. Ludwig-Maximilians-Universität München

    Munich, Germany

    16 h-index

    28 publications

    1.2K citations

1–8 of 777

Venues

  1. Journal of Pharmaceutical Sciences

    86 publications · 5.3K citations

    44

    h-index

  2. Pharmaceutical Research

    53 publications · 3.5K citations

    36

    h-index

  3. International Journal of Pharmaceutics

    44 publications · 2.2K citations

    27

    h-index

  4. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 30 publications · 1.3K citations

    20

    h-index

  5. Biotechnology and Bioengineering

    21 publications · 1.6K citations

    19

    h-index

1–5