Challenges in the development of high protein concentration formulations

Stabilization of protein structure by sugars

Tsutomu Arakawa, Serge N. Timasheff · Biochemistry · 1982 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +7

Salt effects on hydrophobic interactions in precipitation and chromatography of proteins: An interpretation of the lyotropic series

Wayne R. Melander, Csaba Horváth · Archives of Biochemistry and Biophysics · 1977 · 914 citations

Life Sciences, Biochemistry, Chromatographic Analysis +14

Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers

Steven J. Prestrelski, Nicole I. Tedeschi, Tsutomu Arakawa et al. · Biophysical Journal · 1993 · 717 citations · Full text

Life Sciences, Biochemistry, Biophysics +12

Size-Distribution Analysis of Proteins by Analytical Ultracentrifugation: Strategies and Application to Model Systems

Peter Schuck, Matthew A. Perugini, Noreen R. Gonzales et al. · Biophysical Journal · 2002 · 703 citations · Full text

Life Sciences, Biochemistry, Biophysics +13

[3]Theory of protein solubility

Tsutomu Arakawa, Serge N. Timasheff · Methods in enzymology on CD-ROM/Methods in enzymology · 1985 · 364 citations

Natural Sciences, Biochemistry, Chemistry +11