Concepedia

Protein Expression Optimization

Protein Expression Optimization is a systematic approach within protein engineering that involves modulating biological, chemical, and physical parameters to enhance the yield, solubility, and functional integrity of recombinant proteins in host expression systems.

1.7K

Publications

80.6K

Citations

8.1K

Authors

1.7K

Institutions

Publications per year

2017–2026

453

Parents

Children

Publications

1.7K

Efficient selection for high-expression transfectants with a novel eukaryotic vector

Hitoshi Niwa, Ken‐ichi Yamamura, Jun‐ichi Miyazaki · Gene · 1991 · 5.2K citations

, , +15

Challenges in the development of high protein concentration formulations

Zahra Shahrokh, Jun 军 Liu 刘 · Journal of Pharmaceutical Sciences · 2004 · 879 citations

, , +12

Optimality and evolutionary tuning of the expression level of a protein

E. Dekel, Uri Alon · Nature · 2005 · 833 citations

, , +14

Overcoming Expression and Purification Problems of RhoGDI Using a Family of “Parallel” Expression Vectors

Peter Sheffield, Sarah Garrard, Zygmunt S. Derewenda · Protein Expression and Purification · 1999 · 658 citations

, , +12

Designing Repeat Proteins: Well-expressed, Soluble and Stable Proteins from Combinatorial Libraries of Consensus Ankyrin Repeat Proteins

Hans Binz, Michael T. Stumpp, Patrik Forrer et al. · Journal of Molecular Biology · 2003 · 585 citations

, , +16

1–5 of 1.7K

Authors

8.1K

  1. ZX
    Zhinan Xu

    Zhejiang University, China

    11 publications · 343 citations

    11

    h-index

  2. JD
    Jan‐Willem De Gier

    Stockholm University, Sweden

    9 publications · 1.3K citations

    9

    h-index

  3. LH
    Lei Huang

    Zhejiang University, China

    8 publications · 252 citations

    8

    h-index

  4. GD
    Guocheng Du

    Jiangnan University, China

    8 publications · 210 citations

    8

    h-index

  5. DM
    Diethard Mattanovich

    BOKU University, Austria

    7 publications · 440 citations

    7

    h-index

1–5 of 8.1K

Institutions

1.7K

  1. Jiangnan University

    Wuxi, China

    21 h-index

    175 publications

    5.6K citations

  2. Chinese Academy of Sciences

    Beijing, China

    21 h-index

    125 publications

    5.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    95 publications

    4.7K citations

  4. Zhejiang University

    Hangzhou, China

    18 h-index

    121 publications

    3.8K citations

  5. Stockholm University

    Stockholm, Sweden

    17 h-index

    71 publications

    10K citations

  6. KTH Royal Institute of Technology

    Stockholm, Sweden

    15 h-index

    77 publications

    5.1K citations

  7. Imperial College London

    London, United Kingdom

    15 h-index

    38 publications

    3.2K citations

  8. East China University of Science and Technology

    Shanghai, China

    14 h-index

    64 publications

    2.6K citations

1–8 of 1.7K

Venues

  1. Protein Expression and Purification

    234 publications · 9.3K citations

    47

    h-index

  2. Microbial Cell Factories

    65 publications · 3.7K citations

    36

    h-index

  3. Applied Microbiology and Biotechnology

    93 publications · 3.2K citations

    33

    h-index

  4. Biotechnology and Bioengineering

    52 publications · 3.3K citations

    31

    h-index

  5. Journal of Biotechnology

    61 publications · 2.2K citations

    27

    h-index

1–5