Concepedia

Glycosylation Engineering

Glycosylation Engineering is a methodological framework in recombinant protein production that entails the targeted modification of glycosylation pathways in host cell lines to optimize the quality, stability, and biological activity of expressed therapeutic proteins.

505

Publications

27K

Citations

2.8K

Authors

681

Institutions

Publications per year

2017–2026

155

Parents

Publications

505

Generation of glyco‐engineered <i>Nicotiana benthamiana</i> for the production of monoclonal antibodies with a homogeneous human‐like <i>N</i>‐glycan structure

Richard Strasser, Johannes Stadlmann, Matthias Schähs et al. · Plant Biotechnology Journal · 2008 · 523 citations · Full text

, , +17

Humanization of Yeast to Produce Complex Terminally Sialylated Glycoproteins

Stephen R. Hamilton, Robert C. Davidson, Natarajan Sethuraman et al. · Science · 2006 · 501 citations

, , +17

Species-specific variation in glycosylation of IgG: evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeutics

T. Shantha Raju, John B. Briggs, Sarah Borge et al. · Glycobiology · 2000 · 455 citations

, , +17

A novel promoter for the efficient construction of 1,2-trans linkages in glycoside synthesis, using thioglycosides as glycosyl donors

Péter Fügedi, Per J. Garegg · Carbohydrate Research · 1986 · 407 citations

, , +16

Production of Complex Human Glycoproteins in Yeast

Stephen R. Hamilton, Piotr Bobrowicz, Beata Bobrowicz et al. · Science · 2003 · 403 citations

, , +17

1–5 of 505

Authors

2.8K

  1. NC
    Nico Callewaert

    Ghent University, Belgium

    12 publications · 1.1K citations

    12

    h-index

  2. CW
    Chi‐Huey Wong

    Scripps Research Institute, United States

    9 publications · 657 citations

    9

    h-index

  3. FA
    Friedrich Altmann

    BOKU University, Austria

    9 publications · 582 citations

    9

    h-index

  4. HS
    Herta Steinkellner

    BOKU University, Austria

    9 publications · 1.1K citations

    9

    h-index

  5. MP
    Matthew P. DeLisa

    Cornell University, United States

    8 publications · 777 citations

    8

    h-index

1–5 of 2.8K

Institutions

681

  1. BOKU University

    Vienna, Austria

    19 h-index

    98 publications

    8.2K citations

  2. Ghent University

    Ghent, Belgium

    18 h-index

    83 publications

    6.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    79 publications

    4.5K citations

  4. Cornell University

    Ithaca, United States

    13 h-index

    59 publications

    4.9K citations

  5. ETH Zurich

    Zurich, Switzerland

    13 h-index

    48 publications

    4K citations

  6. Chinese Academy of Sciences

    Beijing, China

    11 h-index

    50 publications

    3.1K citations

  7. Jiangnan University

    Wuxi, China

    11 h-index

    47 publications

    1.5K citations

  8. University of Oxford

    Oxford, United Kingdom

    8 h-index

    55 publications

    4.4K citations

1–8 of 681

Venues

  1. Biotechnology and Bioengineering

    26 publications · 2K citations

    21

    h-index

  2. Glycobiology

    16 publications · 1.4K citations

    16

    h-index

  3. Journal of Biotechnology

    16 publications · 639 citations

    13

    h-index

  4. Applied Microbiology and Biotechnology

    10 publications · 356 citations

    10

    h-index

  5. Biotechnology Progress

    10 publications · 468 citations

    10

    h-index

1–5