T. Shantha Raju

Species-specific variation in glycosylation of IgG: evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeutics

T. Shantha Raju, John B. Briggs, Sarah Borge et al. · Glycobiology · 2000 · 452 citations

Glycobiology, Immunology, Molecular Biology +22

Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality

Bernard J. Scallon, Susan H. Tam, Stephen G. McCarthy et al. · Molecular Immunology · 2006 · 380 citations

Glycoproteomics, Protein Glycosylation, Autoimmune Disease +14

Expression of full-length immunoglobulins in Escherichia coli: rapid and efficient production of aglycosylated antibodies

Laura Simmons, Dorothea Reilly, Laura Klimowski et al. · Journal of Immunological Methods · 2002 · 289 citations

Protein Expression, Medicine, Glycobiology +10

Structure-based engineering of a monoclonal antibody for improved solubility

Sheng‐Jiun Wu, Jinquan Luo, Karyn T. O’Neil et al. · Protein Engineering Design and Selection · 2010 · 180 citations

Galactosylation variations in marketed therapeutic antibodies

T. Shantha Raju, Robert E. Jordan · mAbs · 2012 · 123 citations · Full text

Glycobiology, Immunology, Pathology +18