mRNA Stability Optimization is a computational or experimental method aimed at enhancing the intracellular persistence of messenger RNA transcripts by minimizing degradation rates, thereby increasing translational efficiency and protein yield in recombinant expression systems.
34
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2017–2026
18
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34
Algorithm for optimized mRNA design improves stability and immunogenicity
He Zhang, Liang Zhang, Ang Lin et al. · Nature · 2023 · 444 citations · Full text
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1–5 of 195
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84
Jiangnan University
Wuxi, China
3 h-index
20 publications
412 citations
Oregon State University
Corvallis, United States
2 h-index
8 publications
1.9K citations
Innovation Center of NanoMedicine
Kawasaki, Japan
2 h-index
4 publications
179 citations
University of Rochester Medical Center
Rochester, United States
2 h-index
2 publications
464 citations
Eterna Massive Open Laboratory
Stanford, United States
2 h-index
9 publications
2.1K citations
Stanford University
Stanford, United States
2 h-index
38 publications
8.8K citations
China Pharmaceutical University
Nanjing, China
2 h-index
14 publications
1.5K citations
University at Buffalo, State University of New York
Buffalo, United States
2 h-index
2 publications
429 citations
1–8 of 84
Venues
- Biotechnology and Bioengineering
2 publications · 41 citations
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- BioTechniques
2 publications · 42 citations
2
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- Archives of Biochemistry and Biophysics
ABB · 2 publications · 47 citations
2
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- Journal of Biotechnology
2 publications · 37 citations
2
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- Bioconjugate Chemistry
1 publications · 155 citations
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