Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques

Frank Liang, Gustaf Lindgren, Ang Lin, +11

Molecular Therapy

Algorithm for optimized mRNA design improves stability and immunogenicity

He Zhang, Liang Zhang, Ang Lin, +13

Nature

Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo

Maria Vono, Ang Lin, Anna Norrby‐Teglund, +3

Blood

Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation

Luca Cassetta, Kirsten Bruderek, Joanna Skrzeczyńska-Moncznik, +40

Journal for ImmunoTherapy of Cancer

Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study

Shuai Yuan, Paul Carter, Maria Bruzelius, +6

EBioMedicine

Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity

Sebastian Ols, Lifei Yang, Elizabeth A. Thompson, +8

Cell Reports

Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells

Gustaf Lindgren, Sebastian Ols, Frank Liang, +11

Frontiers in Immunology

Immune ActivationAdaptive Immune SystemMrna VaccinesImmunologyHumoral Response +15

A core-shell structured COVID-19 mRNA vaccine with favorable biodistribution pattern and promising immunity

Ren Yang, Yao Deng, Baoying Huang, +23

Signal Transduction and Targeted Therapy

EngineeringImmunologyCovid-19 VaccinesPromising Vaccine CandidateBiomedical Engineering +15

Functional monocytic myeloid-derived suppressor cells increase in blood but not airways and predict COVID-19 severity

Sara Falck‐Jones, Sindhu Vangeti, Meng Yu, +19

Journal of Clinical Investigation

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates

Virginia M. Stone, Minna M. Hankaniemi, Olli H. Laitinen, +9

Science Advances