Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

Luigi Warren, Philip D. Manos, Tim Ahfeldt et al. · Cell stem cell · 2010 · 2.6K citations · Full text

Life Sciences, Biotechnology, Genetics +17

Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA

Katalin Karikó, Michael Buckstein, Houping Ni et al. · Immunity · 2005 · 2.6K citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

Lena M. Kranz, Mustafa Diken, Heinrich Haas et al. · Nature · 2016 · 1.7K citations

Life Sciences, Immunology, Oncology +17

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

Jérôme Cros, Nicolas Cagnard, Kevin Woollard et al. · Immunity · 2010 · 1.2K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes

Norbert Pardi, Steven Tuyishime, Hiromi Muramatsu et al. · Journal of Controlled Release · 2015 · 1K citations

Pharmacy, Molecular Biology, Molecular Pharmaceutics +17