Concepedia

Antigen Presenting Cells

Antigen Presenting Cells is a specialized type of immune cell that belongs to the broader category of leukocytes and is functionally distinguished by its ability to process and present antigenic peptides to T cells via major histocompatibility complex molecules, thereby initiating and regulating adaptive immune responses.

8.9K

Publications

721K

Citations

42.3K

Authors

4.7K

Institutions

Publications per year

2017–2026

1.5K

Variants

Apcs

Parents

Publications

8.9K

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine · 2000 · 5.2K citations · Full text

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine · 1994 · 5.2K citations · Full text

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The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

Arash Grakoui, Shannon K. Bromley, Cenk Sumen et al. · Science · 1999 · 3.1K citations

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CTLA-4 Control over Foxp3 <sup>+</sup> Regulatory T Cell Function

Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin et al. · Science · 2008 · 2.9K citations

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CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.

Matthew F. Krummel, James P. Allison · The Journal of Experimental Medicine · 1995 · 2.2K citations · Full text

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1–5 of 8.9K

Authors

42.3K

  1. RM
    Ralph M. Steinman

    Rockefeller University, United States

    42 publications · 14.1K citations

    36

    h-index

  2. ER
    Emil R. Unanue

    Washington University in St. Louis, United States

    35 publications · 3K citations

    27

    h-index

  3. CG
    Carl G. Figdor

    Radboud University Nijmegen, Netherlands

    32 publications · 5.7K citations

    27

    h-index

  4. HY
    Hideo Yagita∥

    Juntendo University, Japan

    25 publications · 2.7K citations

    23

    h-index

  5. PM
    Philippa Marrack

    University of Colorado Denver, United States

    25 publications · 3.6K citations

    22

    h-index

1–5 of 42.3K

Institutions

4.7K

  1. Harvard University

    Cambridge, United States

    92 h-index

    1.3K publications

    151.9K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    87 h-index

    531 publications

    100.5K citations

  3. National Institutes of Health

    Bethesda, United States

    87 h-index

    960 publications

    119.7K citations

  4. Brigham and Women's Hospital

    Boston, United States

    79 h-index

    671 publications

    95.4K citations

  5. Inserm

    Paris, France

    76 h-index

    1.3K publications

    114.1K citations

  6. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    73 h-index

    485 publications

    83.6K citations

  7. National Cancer Institute

    Bethesda, United States

    69 h-index

    535 publications

    59.8K citations

  8. Yale University

    New Haven, United States

    63 h-index

    409 publications

    77.9K citations

1–8 of 4.7K

Venues

  1. The Journal of Experimental Medicine

    552 publications · 126.8K citations

    189

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 448 publications · 59K citations

    136

    h-index

  3. The Journal of Immunology

    JI · 471 publications · 41.2K citations

    103

    h-index

  4. PubMed

    Repository · 650 publications · 35.2K citations

    94

    h-index

  5. European Journal of Immunology

    EJI · 369 publications · 26K citations

    92

    h-index

1–5