CTLA-4 Control over Foxp3 ⁺ Regulatory T Cell Function

Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin, +5

Science

T-regulatory CellImmunologyImmune RegulationRegulatory T CellsImmunotherapy +18

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

Makoto Miyara, Yumiko Yoshioka, Akihiko Kitoh, +15

Immunity

Foxp3 Transcription FactorSystems BiologySignal TransductionDifferentiation DynamicsLymphocyte Development +9

Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood

K. Klocke, Shimon Sakaguchi, Rikard Holmdahl, +1

Proceedings of the National Academy of Sciences

Characterization of human CD25⁺ CD4⁺ T cells in thymus,
cord and adult blood

Kajsa Wing, Ann Ekmark, Helén Karlsson, +2

Immunology

Defective suppression of Th2 cytokines by CD4⁺CD25⁺ regulatory T cells in birch allergics during birch pollen season

Hanna Grindebacke, Kajsa Wing, Anna Andersson, +3

Clinical & Experimental Allergy

Mannan induces ROS-regulated, IL-17A–dependent psoriasis arthritis-like disease in mice

Ia Khmaladze, Tiina Kelkka, Simon Guérard, +7

Proceedings of the National Academy of Sciences

Dynamics of peripheral tolerance and immune regulation mediated by Treg

Shimon Sakaguchi, Kajsa Wing, Tomoyuki Yamaguchi

European Journal of Immunology

Immune ToleranceT-regulatory CellImmunologyImmune RegulationRegulatory T Cells +17

Reactive Oxygen Species Deficiency Induces Autoimmunity with Type 1 Interferon Signature

Tiina Kelkka, Deborah Kienhöfer, Markus Hoffmann, +17

Antioxidants and Redox Signaling

Phenotypic and functional characterization of human CD25⁺ B cells

Mikael Brisslert, Maria Bokarewa, P. Larsson, +3

Immunology

Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression

Tomoyuki Yamaguchi, Ayumi Kishi, Motonao Osaki, +5

Proceedings of the National Academy of Sciences