Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

Makoto Miyara, Yumiko Yoshioka, Akihiko Kitoh, +15

Immunity

Foxp3 Transcription FactorSystems BiologySignal TransductionDifferentiation DynamicsLymphocyte Development +9

The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling

Wataru Amano, Saeko Nakajima, Hayato Kunugi, +12

Journal of Allergy and Clinical Immunology

Signal TransductionCell SignalingCutaneous BiologyReceptor Tyrosine KinaseSignal Transducer +9

Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells

Akihiko Kitoh, Masahiro Ono, Yoshinori Naoe, +9

Immunity

Vivo-suppressive FunctionTranscriptional RegulationSignal TransductionSignaling PathwayCell Regulation +11

Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin

Yohei Natsuaki, Gyohei Egawa, Satoshi Nakamizo, +21

Nature Immunology

InflammationEfficient ActivationAutoimmune DiseaseCutaneous BiologyImmunology +8

IL-17A as an Inducer for Th2 Immune Responses in Murine Atopic Dermatitis Models

Saeko Nakajima, Akihiko Kitoh, Gyohei Egawa, +12

Journal of Investigative Dermatology

InflammationAtopic DermatitisTh2 Immune ResponsesMedicineImmune Regulation +9

Basophils are required for the induction of Th2 immunity to haptens and peptide antigens

Atsushi Otsuka, Saeko Nakajima, Masato Kubo, +11

Nature Communications

Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses

Yu Sawada, Tetsuya Honda, Sho Hanakawa, +18

The Journal of Experimental Medicine

ImmunologyImmune RegulationImmunologic MechanismDermatologyImmunotherapy +19

High fat diet exacerbates murine psoriatic dermatitis by increasing the number of IL-17-producing γδ T cells

Satoshi Nakamizo, Tetsuya Honda, Akimasa Adachi, +10

Scientific Reports

CD8⁺tumor-infiltrating lymphocytes at primary sites as a possible prognostic factor of cutaneous angiosarcoma

Hiroko Fujii, Akiko Arakawa, Daisuke Utsumi, +15

International Journal of Cancer

Cutaneous AngiosarcomaImmunologyAngiosarcoma PatientsPathologyImmunoediting +15

Basophils regulate the recruitment of eosinophils in a murine model of irritant contact dermatitis

Chisa Nakashima, Atsushi Otsuka, Akihiko Kitoh, +8

Journal of Allergy and Clinical Immunology

AllergyPathogenesisImmunologyMurine ModelIrritant Contact Dermatitis +7