Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai, +16

The Journal of Experimental Medicine

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia

The Journal of Experimental Medicine

Dendritic CellImmunologyImmune RegulationSplice VariantImmunologic Mechanism +17

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor <i>Foxp3 </i>

WanJun Chen, Wenwen Jin, Neil J. Hardegen, +5

The Journal of Experimental Medicine

T-regulatory CellImmune RegulationImmunologyRegulatory T CellsCd4 T Cell Responses +16

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

Claire L. Langrish, Yi Chen, Wendy M. Blumenschein, +6

The Journal of Experimental Medicine

PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES

Renato Dulbecco, Marguerite Vogt

The Journal of Experimental Medicine

Molecular VirologyMonkey KidneyPathogenesisViral PathogenesisImmunology +11

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

René de Waal Malefyt, J S Abrams, B Bennett, +2

The Journal of Experimental Medicine

ImmunologyImmune RegulationImmunologic MechanismInnate ImmunityImmune System +17

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

Kensuke Inaba, Muneo Inaba, Nikolaus Romani, +5

The Journal of Experimental Medicine

B lymphocytes secrete antigen-presenting vesicles.

Graça Raposo, Hans W. Nijman, Willem Stoorvogel, +4

The Journal of Experimental Medicine

Protein SecretionSecrete Antigen-presenting VesiclesHumoral ResponseImmunologyExtracellular Microvesicles +18

STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES

Oswald T. Avery, Colin M. MacLeod, Maclyn McCarty

The Journal of Experimental Medicine

Chemical TransformationChemical NatureBacteriologyChemistryAnalytical Ultracentrifugation +17

A STUDY OF FIXATION FOR ELECTRON MICROSCOPY

George E. Palade

The Journal of Experimental Medicine

EngineeringElectron MicroscopyBiochemistryMicroscopyMicroscopy Method +13