Theodore W. Randolph

Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences · 2008 · 578 citations · Full text

Protein Chemistry, Biochemistry, Subvisible Particles +10

Water-in-Carbon Dioxide Microemulsions: An Environment for Hydrophiles Including Proteins

Keith P. Johnston, Kristi L. Harrison, Matthew Clarke et al. · Science · 1996 · 555 citations

Carbon Dioxide, Engineering, Supercritical Fluid Chromatography +13

Hydrogen Bonding between Sugar and Protein Is Responsible for Inhibition of Dehydration-Induced Protein Unfolding

Steven Allison, Byeong S. Chang, Theodore W. Randolph et al. · Archives of Biochemistry and Biophysics · 1999 · 533 citations

Protein Chemistry, Dehydration-induced Protein Unfolding, Biochemistry +6

The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature‐controlled shelf

James A. Searles, John F. Carpenter, Theodore W. Randolph · Journal of Pharmaceutical Sciences · 2001 · 387 citations

Freeze-thaw Cycling, Ice-water System, Engineering +8

Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony‐stimulating factor

Eva Y., Sampathkumar Krishnan, Brent S. Kendrick et al. · Protein Science · 2003 · 335 citations · Full text

Biophysical Modeling, Colloidal Material, Engineering +20