Concepedia

Excipient Formulation Design

Excipient Formulation Design is a systematic scientific approach within pharmaceutical development that constitutes the rational selection and optimization of stabilizing agents in a lyophilized protein product to preserve structural integrity and biological activity during freeze-drying and storage.

107

Publications

4.4K

Citations

456

Authors

183

Institutions

Publications per year

2017–2026

41

Parents

Publications

107

Selection of excipients for melt extrusion with two poorly water-soluble drugs by solubility parameter calculation and thermal analysis

Angus H. Forster, John Hempenstall, Ian G. Tucker et al. · International Journal of Pharmaceutics · 2001 · 394 citations

, , +17

Use of a screening method to determine excipients which optimize the extent and stability of supersaturated drug solutions and application of this system to solid formulation design

Roger Vandecruys, Jef Peeters, Geert Verreck et al. · International Journal of Pharmaceutics · 2007 · 163 citations

, , +16

Use of 2-Hydroxypropyl-β-cyclodextrin as a Solubilizing and Stabilizing Excipient for Protein Drugs

Marcus E. Brewster, Maninder Hora, James W. Simpkins et al. · Pharmaceutical Research · 1991 · 155 citations

, , +12

Enhancement of the solubility, stability and bioaccessibility of quercetin using protein-based excipient emulsions

Xing Chen, David Julian McClements, Yuqing Zhu et al. · Food Research International · 2018 · 151 citations

, , +12

The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules

Tomás Sou, Lisa M. Kaminskas, Tri‐Hung Nguyen et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2012 · 143 citations · Full text

, , +17

1–5 of 107

Authors

456

  1. HH
    Hamed H. El‐Shattawy

    Al-Azhar University, Egypt

    4 publications · 70 citations

    4

    h-index

  2. DL
    Dirk Lochmann

    University of Graz, Austria

    3 publications · 56 citations

    3

    h-index

  3. CC
    Carolina Corzo

    University of Graz, Austria

    3 publications · 56 citations

    3

    h-index

  4. GE
    Garnet E. Peck

    Purdue University West Lafayette, United States

    3 publications · 58 citations

    3

    h-index

  5. SS
    Sharareh Salar-Behzadi

    Research Center Pharmaceutical Engineering (Austria), Austria

    3 publications · 56 citations

    3

    h-index

1–5 of 456

Institutions

183

  1. Purdue University West Lafayette

    West Lafayette, United States

    5 h-index

    9 publications

    197 citations

  2. Al-Azhar University

    Cairo, Egypt

    4 h-index

    4 publications

    70 citations

  3. University of Graz

    Graz, Austria

    3 h-index

    5 publications

    93 citations

  4. Research Center Pharmaceutical Engineering (Austria)

    Graz, Austria

    3 h-index

    15 publications

    282 citations

  5. University College London

    London, United Kingdom

    2 h-index

    6 publications

    272 citations

  6. University of Eastern Finland

    Joensuu, Finland

    2 h-index

    6 publications

    208 citations

  7. Universitat de Barcelona

    Barcelona, Spain

    2 h-index

    9 publications

    170 citations

  8. Trinity College Dublin

    Dublin, Ireland

    2 h-index

    4 publications

    78 citations

1–8 of 183

Venues

  1. International Journal of Pharmaceutics

    20 publications · 1.2K citations

    16

    h-index

  2. Drug Development and Industrial Pharmacy

    10 publications · 304 citations

    10

    h-index

  3. AAPS PharmSciTech

    7 publications · 325 citations

    7

    h-index

  4. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 6 publications · 247 citations

    6

    h-index

  5. Pharmaceutical Research

    5 publications · 298 citations

    5

    h-index

1–5