Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy

Lisa M. Kaminskas, Victoria M. McLeod, Gemma M. Ryan, +6

Journal of Controlled Release

Cancer TherapyLung MetastasesOncologyPolymer-drug ConjugatePharmacology +8

The Impact of Molecular Weight and PEG Chain Length on the Systemic Pharmacokinetics of PEGylated Poly <scp>l</scp>-Lysine Dendrimers

Lisa M. Kaminskas, Ben J. Boyd, Peter Karellas, +4

Molecular Pharmaceutics

Pharmaceutical ScienceEngineeringSystemic PharmacokineticsLarger DendrimersPeg Chain Length +14

A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systems

Lisa M. Kaminskas, Victoria M. McLeod, Brian D. Kelly, +5

Nanomedicine Nanotechnology Biology and Medicine

NanomedicineAntitumor ActivityPolymer-drug ConjugateMedicineDrug Delivery Systems +7

Cationic Poly- <scp>l</scp> -lysine Dendrimers:  Pharmacokinetics, Biodistribution, and Evidence for Metabolism and Bioresorption after Intravenous Administration to Rats

Ben J. Boyd, Lisa M. Kaminskas, Peter Karellas, +3

Molecular Pharmaceutics

PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats

Lisa M. Kaminskas, Jagannath Kota, Victoria M. McLeod, +3

Journal of Controlled Release

Sc AdministrationPharmaceutical ScienceDrug TargetingPolylysine DendrimersPolymer-drug Conjugate +5

The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules

Tomás Sou, Lisa M. Kaminskas, Tri‐Hung Nguyen, +3

European Journal of Pharmaceutics and Biopharmaceutics

ExcipientsPulmonary DeliveryMicro-encapsulationBiomedical EngineeringMulti-component Spray-dried Formulations +3

Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-<scp>l</scp>-lysine Dendrimers

Lisa M. Kaminskas, Brian D. Kelly, Victoria M. McLeod, +4

Molecular Pharmaceutics

Dendrimer DispositionNanomedicinePharmaceutical ScienceDrug TargetingTumor Disposition +11

Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linker

Lisa M. Kaminskas, Brian D. Kelly, Victoria M. McLeod, +4

Journal of Controlled Release

NanomedicineMedicinal ChemistryPegylated Polylysine DendrimersEngineeringDrug Targeting +7

Prediction and Optimization of Pharmacokinetic and Toxicity Properties of the Ligand

Douglas E. V. Pires, Lisa M. Kaminskas, David B. Ascher

Methods in molecular biology

Pharmacokinetic ModelingBiochemistryToxicity PropertiesDrug DiscoveryMedicine +4

Pulmonary Administration of PEGylated Polylysine Dendrimers: Absorption from the Lung versus Retention within the Lung Is Highly Size-Dependent

Gemma M. Ryan, Lisa M. Kaminskas, Brian D. Kelly, +3

Molecular Pharmaceutics

EngineeringLung Versus RetentionPulmonary AdministrationPharmacotherapyBiomedical Engineering +17