Tomás Sou

The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules

Tomás Sou, Lisa M. Kaminskas, Tri‐Hung Nguyen et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2012 · 140 citations

Excipients, Pulmonary Delivery, Micro-encapsulation +5

Investigating the interactions of amino acid components on a mannitol-based spray-dried powder formulation for pulmonary delivery: A design of experiment approach

Tomás Sou, Laurence Orlando, Michelle P. McIntosh et al. · International Journal of Pharmaceutics · 2011 · 58 citations

Pharmaceutical Science, Lung Deposition, Experiment Approach +9

Spray-Dried Influenza Antigen with Trehalose and Leucine Produces an Aerosolizable Powder Vaccine Formulation that Induces Strong Systemic and Mucosal Immunity after Pulmonary Administration

Tomás Sou, David Morton, Mark Williamson et al. · Journal of Aerosol Medicine and Pulmonary Drug Delivery · 2015 · 51 citations

Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

Fadi Soukarieh, Ruiling Liu, Manuel Romero et al. · Frontiers in Chemistry · 2020 · 49 citations · Full text

Model‐Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin

Tomás Sou, Jon Hansen, Edgars Liepinsh et al. · Clinical Pharmacology & Therapeutics · 2020 · 41 citations · Full text

Antimicrobial Chemotherapy, Physiologically-based Pharmacokinetic Modeling, Pharmacodynamic Modeling +20