Ribo Guo

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Silvia Buonamici, Juliet Williams, Michael Morrissey et al. · Science Translational Medicine · 2010 · 553 citations

Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database

Zaneta Nikolovska‐Coleska, Liang Xu, Zengjian Hu et al. · Journal of Medicinal Chemistry · 2004 · 340 citations · Full text

Pharmaceutical Research, Drug Target, Chemoprevention Strategy +19

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Shifeng Pan, Xu Wu, Jiqing Jiang et al. · ACS Medicinal Chemistry Letters · 2010 · 325 citations · Full text

Selective Smoothened Antagonist, Chemoprevention Strategy, Novel Therapy +14

Discovery of Small-Molecule Inhibitors of Bcl-2 through Structure-Based Computer Screening

Istvan Enyedy, Yan Ling, Kassoum Nacro et al. · Journal of Medicinal Chemistry · 2001 · 312 citations · Full text

A crucial requirement for Hedgehog signaling in small cell lung cancer

Luciano G. Martelotto, Martin Peifer, Martin L. Sos et al. · Nature Medicine · 2011 · 246 citations

Tumor Biology, Oncology, Medicine +8