Xu Wu

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

Jun Liu, Shifeng Pan, Mindy H. Hsieh et al. · Proceedings of the National Academy of Sciences · 2013 · 835 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

A Stem Cell–Based Approach to Cartilage Repair

Kristen Johnson, Shoutian Zhu, Matthew S. Tremblay et al. · Science · 2012 · 790 citations

Medicine, Cell Biology, Molecular Biology +17

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Silvia Buonamici, Juliet Williams, Michael Morrissey et al. · Science Translational Medicine · 2010 · 554 citations

Medicine, Oncology, Pharmacology +16

Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors

Lizhi He, Jhih-Hua Jhong, Qi Chen et al. · Cell Reports · 2021 · 349 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Shifeng Pan, Xu Wu, Jiqing Jiang et al. · ACS Medicinal Chemistry Letters · 2010 · 328 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15