Silvia Buonamici

The allosteric inhibitor ABL001 enables dual targeting of BCR–ABL1

Andrew A. Wylie, Joseph Schoepfer, Wolfgang Jahnke et al. · Nature · 2017 · 596 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

Eun Hee Kim, Janine O. Ilagan, Yang Liang et al. · Cancer Cell · 2015 · 569 citations · Full text

Medicine, Genetics, Molecular Genetics +8

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Silvia Buonamici, Juliet Williams, Michael Morrissey et al. · Science Translational Medicine · 2010 · 554 citations

Medicine, Oncology, Pharmacology +16

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

Michael Seiler, Akihide Yoshimi, Rachel Darman et al. · Nature Medicine · 2018 · 510 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

Benjamin J. Thompson, Silvia Buonamici, Maria Luisa Sulis et al. · The Journal of Experimental Medicine · 2007 · 486 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14