Akihide Yoshimi

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Luisa Cimmino, Igor Dolgalev, Yubao Wang et al. · Cell · 2017 · 684 citations · Full text

Hematological Malignancy, Medicine, Mixed-phenotype Acute Leukemia +6

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

Michael Seiler, Akihide Yoshimi, Rachel Darman et al. · Nature Medicine · 2018 · 491 citations · Full text

Tumor Biology, Medicine, Rna Splicing +9

Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia

Eric Wang, Sydney X. Lu, Alessandro Pastore et al. · Cancer Cell · 2019 · 364 citations · Full text

Rna-binding Protein Network, Rna Binding Proteins, Rna Structure Prediction +3

Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins

Stanley Chun-Wei Lee, Heidi Dvinge, Eun Hee Kim et al. · Nature Medicine · 2016 · 352 citations · Full text

Hematological Malignancy, Rna Processing, Systems Biology +7

Spliceosomal disruption of the non-canonical BAF complex in cancer

Daichi Inoue, Guo-Liang Chew, Bo Liu et al. · Nature · 2019 · 227 citations

Spliceosomal Disruption, Medicine, Cancer Genetics +3