Juliet Williams

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

Hui Gao, Joshua M. Korn, Stéphane Ferretti et al. · Nature Medicine · 2015 · 1.4K citations

Tumor Biology, Radiology, Oncology +10

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Silvia Buonamici, Juliet Williams, Michael Morrissey et al. · Science Translational Medicine · 2010 · 553 citations

The metabolic function of cyclin D3–CDK6 kinase in cancer cell survival

Haizhen Wang, Brandon Nicolay, Joel M. Chick et al. · Nature · 2017 · 348 citations · Full text

Tumor Biology, Oncology, Metabolic Function +12

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Shifeng Pan, Xu Wu, Jiqing Jiang et al. · ACS Medicinal Chemistry Letters · 2010 · 325 citations · Full text

Selective Smoothened Antagonist, Chemoprevention Strategy, Novel Therapy +14

Identification of a small molecule inhibitor of the hedgehog signaling pathway: Effects on basal cell carcinoma-like lesions

Juliet Williams, Oivin Guicherit, Beatrice I. Zaharian et al. · Proceedings of the National Academy of Sciences · 2003 · 298 citations · Full text

Signaling Pathway, Oncogenic Agent, Medicine +11