Jiqing Jiang

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen et al. · Journal of Medicinal Chemistry · 2013 · 405 citations · Full text

Chemoprevention Strategy, Pharmacotherapy, Structure–activity Relationships +21

Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK

Anna Galkin, Jonathan S. Melnick, Sung Joon Kim et al. · Proceedings of the National Academy of Sciences · 2006 · 375 citations · Full text

Drug Target, Immunology, Cell Death +22

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Shifeng Pan, Xu Wu, Jiqing Jiang et al. · ACS Medicinal Chemistry Letters · 2010 · 325 citations · Full text

Selective Smoothened Antagonist, Chemoprevention Strategy, Novel Therapy +14

Antibiotic optimization via in vitro glycorandomization

Xun Fu, Christoph Albermann, Jiqing Jiang et al. · Nature Biotechnology · 2003 · 213 citations

Engineering, Antibiotic Optimization, Antibiotics +9

Natures Carbohydrate Chemists The Enzymatic Glycosylation of Bioactive Bacterial Metabolites

Jon S. Thorson, Thomas J. Hosted, Jiqing Jiang et al. · Current Organic Chemistry · 2001 · 164 citations