Jon S. Thorson

A genomics-guided approach for discovering and expressing cryptic metabolic pathways

Emmanuel Zazopoulos, Ke-xue Huang, Alfredo Staffa et al. · Nature Biotechnology · 2003 · 316 citations

Metabolic Network, Functional Genomics, Engineering +14

Exploiting the Reversibility of Natural Product Glycosyltransferase-Catalyzed Reactions

Changsheng Zhang, Byron R. Griffith, Qiang Fu et al. · Science · 2006 · 289 citations

Biosynthesis, Bioorganic Chemistry, Engineering +14

The Calicheamicin Gene Cluster and Its Iterative Type I Enediyne PKS

Joachim Ahlert, Erica M. Shepard, Natalia Lomovskaya et al. · Science · 2002 · 288 citations

Biosynthesis, Protein Expression, Calicheamicin Gene Cluster +15

Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution

Gavin J. Williams, Changsheng Zhang, Jon S. Thorson · Nature Chemical Biology · 2007 · 264 citations

Biosynthesis, Bioorganic Chemistry, Engineering +10

Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization

Joseph M. Langenhan, Noël R. Peters, Ilia A. Guzei et al. · Proceedings of the National Academy of Sciences · 2005 · 235 citations · Full text