Bei Chen

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen et al. · Journal of Medicinal Chemistry · 2013 · 405 citations · Full text

Chemoprevention Strategy, Pharmacotherapy, Structure–activity Relationships +21

Bitter and sweet taste receptors regulate human upper respiratory innate immunity

Robert J. Lee, Jennifer M. Kofonow, Philip L. Rosen et al. · Journal of Clinical Investigation · 2014 · 403 citations · Full text

Asthma, Microbial Pathogens, Lung Inflammation +16

Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release

Ping Zhou, Yoshihisa Takaishi, Hong‐Quan Duan et al. · Phytochemistry · 2000 · 174 citations

Medicinal Chemistry, Anti-hiv Activity, Cytokine Release +9

Influence of Histidine on the Stability and Physical Properties of a Fully Human Antibody in Aqueous and Solid Forms

Bei Chen, Raquel Bautista, Kwok Yu et al. · Pharmaceutical Research · 2003 · 157 citations

Solid Forms, Immunocytochemical Technique, Allergy +11

Solitary chemosensory cells are a primary epithelial source of IL-25 in patients with chronic rhinosinusitis with nasal polyps

Michael A. Kohanski, Alan D. Workman, Neil N. Patel et al. · Journal of Allergy and Clinical Immunology · 2018 · 155 citations · Full text

Asthma, Cytokine, Nasal Polyps +10