Istvan Enyedy

Discovery of Small-Molecule Inhibitors of Bcl-2 through Structure-Based Computer Screening

Istvan Enyedy, Yan Ling, Kassoum Nacro et al. · Journal of Medicinal Chemistry · 2001 · 312 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +12

Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism

D.J. Marcotte, Weike Zeng, Jean‐Christophe Hus et al. · Bioorganic & Medicinal Chemistry · 2013 · 238 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Can we use docking and scoring for hit-to-lead optimization?

Istvan Enyedy, William J. Egan · Journal of Computer-Aided Molecular Design · 2008 · 95 citations

Pharmacy, Medicinal Chemistry, Lead Optimization +10

Pharmacophore-Based discovery of substituted pyridines as novel dopamine transporter inhibitors

Istvan Enyedy, Sukumar Sakamuri, Wahiduz A. Zaman et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 87 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and evaluation of the sunflower derived trypsin inhibitor as a potent inhibitor of the type II transmembrane serine protease, matriptase

Ya‐Qiu Long, Sheau-Ling Lee, Chen‐Yong Lin et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 83 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11