Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, Fábio Camargo Abdalla, Hagai Abeliovich, +1232

Autophagy

MitophagyParticular Autophagy AssaysImmunologyCytoskeletonMultiple Assays +17

MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells

Qing Ji, Xinbao Hao, Min Zhang, +10

PLoS ONE

Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation

Defang Li, Jin Liu, Baosheng Guo, +31

Nature Communications

Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

Qing Ji, Xinbao Hao, Yang Meng, +4

BMC Cancer

Bcl-2:Beclin 1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch.

Rebecca T. Marquez, Liang Xu

PubMed

Cell AutophagyMitophagySignal TransductionMedicineApoptosis +13

Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database

Zaneta Nikolovska‐Coleska, Liang Xu, Zengjian Hu, +10

Journal of Medicinal Chemistry

Pharmaceutical ResearchDrug TargetChemoprevention StrategyApoptosisCell Death +17

In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis

Jatin Roper, Tuomas Tammela, Naniye Mallı Cetinbas, +31

Nature Biotechnology

Tumor HeterogeneityVivo Genome EditingMedicineColorectal CancerCancer Genomics +7

Systemic tumor-targeted gene delivery by anti-transferrin receptor scFv-immunoliposomes.

Liang Xu, Chengcheng Huang, Wei‐Qun Huang, +7

PubMed

Anti-tfr ScfvCell-based Drug DeliveryDrug TargetingAnti-transferrin Receptor Scfv-immunoliposomesLipid-tagged Scfv +13

Transferrin-Liposome-Mediated Systemic p53 Gene Therapy in Combination with Radiation Results in Regression of Human Head and Neck Cancer Xenografts

Liang Xu, Kathleen F. Pirollo, Wenhua Tang, +2

Human Gene Therapy

Ligand-liposome Delivery SystemPathologyMolecular BiologyGene DeliveryTumor Biology +20

A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2–Beclin1 interaction at endoplasmic reticulum

Jiqin Lian, Xiong-Zhi Wu, Fengtian He, +6

Cell Death and Differentiation

Cell AutophagyBcl-2–beclin1 InteractionMedicineApoptosisAutophagy +9