Zaneta Nikolovska‐Coleska

Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction

Ke Ding, Yipin Lu, Zaneta Nikolovska‐Coleska et al. · Journal of Medicinal Chemistry · 2006 · 692 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Sanjeev Shangary, Dongguang Qin, Donna McEachern et al. · Proceedings of the National Academy of Sciences · 2008 · 656 citations · Full text

Medicine, Oncology, Pharmacology +13

Structure-Based Design of Potent Non-Peptide MDM2 Inhibitors

Ke Ding, Yipin Lu, Zaneta Nikolovska‐Coleska et al. · Journal of the American Chemical Society · 2005 · 649 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization

Zaneta Nikolovska‐Coleska, Renxiao Wang, Xueliang Fang et al. · Analytical Biochemistry · 2004 · 557 citations

Life Sciences, Biochemistry, Molecular Biology +15

Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database

Zaneta Nikolovska‐Coleska, Liang Xu, Zengjian Hu et al. · Journal of Medicinal Chemistry · 2004 · 342 citations · Full text

Pharmacy, Oncology, Pharmacology +16