Sanjeev Shangary

Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction

Ke Ding, Yipin Lu, Zaneta Nikolovska‐Coleska et al. · Journal of Medicinal Chemistry · 2006 · 681 citations · Full text

Combinatorial Chemistry, Mdm2-p53 Interaction, Chemoprevention Strategy +19

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Sanjeev Shangary, Dongguang Qin, Donna McEachern et al. · Proceedings of the National Academy of Sciences · 2008 · 650 citations · Full text

SAR405838: An Optimized Inhibitor of MDM2–p53 Interaction That Induces Complete and Durable Tumor Regression

Shaomeng Wang, Wei Sun, Yujun Zhao et al. · Cancer Research · 2014 · 335 citations · Full text

Structure-Based Design of Potent Small-Molecule Inhibitors of Anti-Apoptotic Bcl-2 Proteins

Guoping Wang, Zaneta Nikolovska‐Coleska, Chao‐Yie Yang et al. · Journal of Medicinal Chemistry · 2006 · 293 citations · Full text

SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP

Jianfeng Lü, Longchuan Bai, Haiying Sun et al. · Cancer Research · 2008 · 200 citations · Full text

Tumor Regression, Apoptosis Protein, Apoptosis +18